Chronic mild stress induces anhedonic behavior and changes in glutamate release, BDNF trafficking and dendrite morphology only in stress vulnerable rats. The rapid restorative action of ketamine
Depression is a debilitating mental disease, characterized by persistent low mood and anhedonia.Stress represents a major environmental risk factor for depression; the complex interaction of stress with genetic factors results in different individual vulnerability or resilience to the sansamp rack disorder.Dysfunctions of the glutamate system have